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http://bit.ly/BWNewsUpdatesA process engineering approach based in similarity, not difference.

It was adopted by Pfizer and incorporated into the delivered scheme.“The layout, space and light in the milling building is superb,” said Pfizer’s Senior Director of Operations..

The Singapore API plant is the 2024 FOYA Category Winner for Operations, Project Execution.This is thanks to the whole project team's successful delivery of a large and complex project ahead of schedule and under budget during a global pandemic.. GSK Parma Attachment Inhibitor: meeting a life-saving need.Aiming to introduce manufacturing capability into GSK’s Parma site for Fostemsavir (a life-saving HIV drug for patients with limited or no other treatment options available), this project’s brief was ambitious.. To maintain supply while the drug was in development and clinical trials, GSK had to build and commission a brand new facility in a shorter timeframe than had ever been achieved before.. As lead designer, Bryden Wood formed a collaborative team with external partners and client representatives to capture functional requirements in “Chip” models that could be rapidly configured to allow many design options to be evaluated in a short time..

The ability to undertake rapid digital optioneering was particularly important as forecast demand volumes were uncertain and clinical manufacturing requirements for the drug were still being developed during the design phase.We developed a capacity model in-house to inform decisions around unit operations and scale..

The final design concept was deliberately simple.

Process spaces were housed on a single level, raised above the ground to meet flood protection requirements.Homo erectus, our earlier cousin, could do all these things and spread out globally surviving and developing for a million years.

Interestingly, Homo sapiens, us, developing later and in parallel were a bit smaller.The current view is that the advantage was size and reduced testosterone leading to less aggression and the ability to create and work in large social groups.. Mammals, themselves really came into their own after the last mass-extinction event some 65 million years ago.

They were overall much smaller than the dominant animals - the dinosaurs - and their size and adaptability is seen as a key feature for their survival and thriving.. Moving away from the natural world into the world designed by Homo sapiens, there is a very different approach to scale.Things are scaled up and down from the size of a human.